The first thing I like to do is to get as little sleep as possible the night before I fly, this way by the time I get to the plane I can hopefully just go to sleep and wake up at my destination. I only recommend this if you are able to perform any tasks you need to do before your flight. If you have to drive for 5 hrs first you may want to get a good night sleep, and maybe take some Tylenol pm or something else to make you drowsy. Many people like to get a little drunk on a flight, I am not one of them, but if it helps you relax and get some sleep then I say go for it, just dont allow yourself to drink to the point where you become an obnoxious drunk on a plane.
My next tip is to get to the airport 3 hours in advance, this is for 2 reasons. By getting there so early I am always one of if not the first to actually check in for my flight, which usually gets me a good seat, and I dont have to wait in long lines. The other reason for always getting t the Air port at least 3 hrs before your flight is, if you check in early you cant get bumped from the plane, the people who get there last minute sometime here the words overbooked.
Things to pack in your carry...