Hair growth patterns in humans depend upon the interaction of natural cycles of hair growth and hair loss. The hair growth cycles follow a structured process that has 3 phases. These 3 phases are anagen (the growth phase), catagen (the transitional phase) and telogen (The resting Phase). The hair is actively growing only in the anagen phase where it increases in length by about 1 cm in every 28 days. Hair loss occurs when the hair is in the resting phase. Most hairs in the resting phase lie in the skin separated from the dermal papilla at its base. Since the hair is not held tightly at its root, it is prone to shedding at any point.
The entire hair growth cycle is under the influence of hormones and their metabolic products. Dihydrotestosterone is the most important metabolite that plays the major role in retarding the hair growth and affecting hair loss. Accumulation of DHT (dihydrotestosterone) within the hair follicle is considered to be the main cause of hair loss.
The DHT mediates the hair loss through its direct action on the androgenic receptors in human scalp tissue. It interrupts the normal physiologic environment and function of the hair follicles....
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