Men have been experimenting with weird fuel concoctions since man tamed fire. Even from the beginnings of fire it was obvious that the hotter fuel would give the best results. This more than translates the right fuel would mean top speeds for racing cars. After all the best burning fuel would give the faster camshafts to win the race. Eve with the technologically advanced fuels we still do not know what the upper limits of performance potential might be with the most potent fuels.
The conventional automotive piston engine was designed to run on straight gasoline fuels. The major problems in this case was to get sufficient fuel octane ratings to prevent excessive detonation , or knock , to prevent excessive detonation, Detonation of course is a sudden , uncontrolled explosion of the last part of the gas-oil mixture. This uncontrolled explosion of gas in your engine, not only reduces power, but can easily cause engine damage, breaking piston rings and even the pistons themselves. Simply put if you have enough octane to prevent detonation there is not much else that can be done to get additional power out of gasoline.
It is a different story when you are free to use...