There are many factors that go into home building costs and it can be huge task to even come out with an estimate.
The quickest way to estimate home building costs is to find similar houses in the area that has the same overall look and size of one that you want to build. Then take the selling price, minus the cost of the land and you will have a rough and quick estimate of the construction cost. This is, of course not an exact science, but by following this basic rule you will be able to get a rough estimate.
If the house that you are comparing with was built a few years ago, then you should factor in the appreciation cost due to increase in the cost of labor and materials at between 2 to 5% per annum.
Home building costs can be further influence by the interior feature of the home. Lets say you want a completely furnished basement and the house than you are using as a reference does not. You should factor this into the cost estimate. A little here and there can add up to thousands of dollars.
Another way is to seek the help of a construction company. If you show them the type of house that you are interested in they should be able to respond to...