Autism is a complex neurological disorder that involves abnormalities at the level of the central nervous system. Although the specific causes of autism in remain unknown, it seems that acquired or inherited genetic dysfunctions have a very important role in the occurrence of the syndrome in people. Recent experiments conducted on mice have proved that there is a clear connection between genetic factors and abnormal behaviors characteristic to ASD (autism spectrum disorders). By deleting the PTEN gene in some areas of the brain of mice, scientists have been able to trigger symptoms that are very similar to those generated by autism in humans.
Although the experiment cant explain the exact phenomenon that leads to the development of autism in people, the results suggest that autistic people present abnormalities in a region of the brain called hippocampus. When researchers deleted the PTEN gene in the hippocampus of mice, the results were remarkable. The mice with the PTEN gene deleted quickly began to follow the behavioral patterns generated by autism in humans. The abnormal mice showed clear signs of impairment at the levels of social interactions, rapidly losing their...
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