American Heart Association (AHA) spokeswoman Barbara V. Howard, PhD, says despite the confusing findings, it is clear that keeping cholesterol under control is one of the best ways to avoid heart attack and stroke. Howard leads the AHA council on nutrition, physical activity, and metabolism and is president of MedStar Research Institute in Hyattsville, Md.
“Start with diet, exercise, and weight control — and if that doesn’t do it, medication probably will,” she tells WebMD.
“There is no question that lowering cholesterol also lowers stroke risk..”
Lewington and colleagues agree that the public health message is unambiguous.
“Treatment should be guided principally by the definitive evidence from randomized trials, [showing] that Statins (Lipitor, Zocor) substantially reduce not only coronary event rates but also total stroke rates in patients with a wide range of ages and blood pressures,” they write. High cholesterol is a major risk factor for death from heart disease, but its impact on stroke death is less clear, a new analysis combining 61 studies confirms.
In one of the largest evaluations...