If your child has recurring illnesses, don’t simply brush off these ailments as normal childhood health problems. He or she may have a serious underlying disease.
Primary immunodeficiency, or PI, is a genetic defect that can compromise a child’s immune system, leading to an increased susceptibility to certain infectious illnesses. There are more than 100 types of PI; each has somewhat different symptoms, depending on which parts of the immune system are affected. Some deficiencies are deadly, while others are mild.
In children with PI, usual childhood illnesses occur frequently and can drag on and become chronic despite the use of antibiotics. If a child suffers from eight or more ear infections or two or more serious sinus infections within a year, he or she could have a serious form of PI. Other warning signs are failure to gain weight or grow normally and a proven family history of PI.
While there are more than
1 million children and young adults in the United States affected by PI, experts estimate that 70 percent to 90 percent of those with the disease go undiagnosed. Without diagnosis and treatment, constant infections can...
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